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1

Resonant mirror biosensor detection method based on yessotoxin–phosphodiesterase interactions

María-José Pazos, Amparo Alfonso, Mercedes R. Vieytes, Takeshi Yasumoto, Juan M. Vieites, Luis M. Botana

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

2

Acute Oral Toxicity of Tetrodotoxin in Mice: Determination of Lethal Dose 50 (LD50) and No Observed Adverse Effect Level (NOAEL)

Abal, Paula, Louzao, M., Antelo, Alvaro, Alvarez, Mercedes, Cagide, Eva, Vilariño, Natalia, Vieytes, Mercedes, Botana, Luis

Journal:

Year:

2017

Language:

english

File:

PDF, 567 KB

english, 2017

3

Two years experience on the use of molecular biology techniques in neuroinfections. Preliminary cohort at Maciel Hospital

Taborda, A., Rey, R., Bruno, G., Vaucher, A., Grill, F., Vieytes, M., Galiana, A.

Journal:

International Journal of Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 168 KB

english, 2018

4

Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection

Vilariño, Natalia, Louzao, M., Abal, Paula, Cagide, Eva, Carrera, Cristina, Vieytes, Mercedes, Botana, Luis

Journal:

Year:

2018

Language:

english

File:

PDF, 1.28 MB

english, 2018

5

Canning Process that Diminishes Paralytic Shellfish Poison in Naturally Contaminated Mussels (Mytilus galloprovincialis)

VIEITES, J. M., BOTANA, L. M., VIEYTES, M. R., LEIRA, F. J.

Journal:

Journal of Food Protection

Year:

1999

Language:

english

File:

PDF, 117 KB

english, 1999

6

Detoxification agents based on magnetic nanostructured particles as a novel strategy for mycotoxin mitigation in food

González-Jartín, Jesús M., de Castro Alves, Lisandra, Alfonso, Amparo, Piñeiro, Y., Yáñez Vilar, Susana, González Gomez, Manuel, Vargas Osorio, Zulema, Sainz, María J., Vieytes, Mercedes R., Rivas, J.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.44 MB

english, 2019

7

Polyclonal Campylobacter fetus infections among unrelated patients, Montevideo, Uruguay, 2013-2018

Costa, Daniela, Betancor, Laura, Gadea, Pilar, Cabezas, Laura, Caiata, Leticia, Palacio, Rosario, Seija, Verónica, Galiana, Antonio, Vieytes, Mariela, Cristophersen, Inés, Calleros, Lucía, Iraola, Gre

Journal:

Clinical Infectious Diseases

Year:

2019

Language:

english

File:

PDF, 540 KB

english, 2019

8

New protocol to obtain spirolides from Alexandrium ostenfeldii cultures with high recovery and purity

Paz Otero, Amparo Alfonso, Carmen Alfonso, Mercedes R. Vieytes, M. Carmen Louzao, Ana M. Botana, Luis M. Botana

Journal:

Biomedical Chromatography

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

9

Effects of environmental regimens on the toxin profile of Alexandrium ostenfeldii

Paz Otero, Amparo Alfonso, Mercedes R. Vieytes, Ana G. Cabado, Juan M. Vieites, Luis M. Botana

Journal:

Environmental Toxicology and Chemistry

Year:

2010

Language:

english

File:

PDF, 624 KB

english, 2010

10

Calcium-pH Crosstalks in the human mast cell line HMC-1: Intracellular alkalinization activates calcium extrusion through the plasma membrane Ca2+-ATPase

Octavio Pernas-Sueiras, Amparo Alfonso, Mercedes R. Vieytes, Alberto Orfao, Luis Escribano, Sánchez-Jiménez Francisca, Luis M. Botana

Journal:

Journal of Cellular Biochemistry

Year:

2006

Language:

english

File:

PDF, 234 KB

english, 2006

11

PKC and cAMP positively modulate alkaline-induced exocytosis in the human mast cell line HMC-1

Octavio Pernas-Sueiras, Amapro Alfonso, Mercedes R. Vieytes, Luis M. Botana

Journal:

Journal of Cellular Biochemistry

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

12

Calcium oscillations induced by gambierol in cerebellar granule cells

E. Alonso, C. Vale, M. Sasaki, H. Fuwa, Y. Konno, S. Perez, M.R. Vieytes, L.M. Botana

Journal:

Journal of Cellular Biochemistry

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

13

Amiloride-dependent transport is the main mechanism implicated in sodium iinflux regulation in rat mast cells

Ana G. Cabado, Mercedes R. Vieytes, Luis M. Botana

Journal:

Journal of Cellular Physiology

Year:

1993

Language:

english

File:

PDF, 378 KB

english, 1993

14

Effect of ion composition on the changes in membrane potential induced with several stimuli in rat mast cells

Ana G. Cabado, Mercedes R. Vieytes, Luis M. Botana

Journal:

Journal of Cellular Physiology

Year:

1994

Language:

english

File:

PDF, 839 KB

english, 1994

15

Mast cell exocytosis can be triggered by ammonium chloride with just a cytosolic alkalinization and no calcium increase

O. Pernas-Sueiras, A. Alfonso, M.R. Vieytes, L.M. Botana

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

16

D-glucose transporter on mussel mantle cell membranes: Effect of sodium and phlorizin

M. C. Louzao, M. R. Vieytes, L. M. Botana

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1993

Language:

english

File:

PDF, 506 KB

english, 1993

17

Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin

Carmen Vale, Amparo Alfonso, Cristina Suñol, Mercedes R. Vieytes, Luis M. Botana

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 800 KB

english, 2006

18

Role of the plasma membrane calcium adenosine triphosphatase on domoate-induced intracellular acidification in primary cultures of cerebelar granule cells

Carmen Vale-González, Amparo Alfonso, Cristina Suñol, Mercedes R. Vieytes, Luis M. Botana

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 252 KB

english, 2006

19

Effects of the marine phycotoxin palytoxin on neuronal pH in primary cultures of cerebellar granule cells

Carmen Vale-González, Belén Gómez-Limia, Mercedes R. Vieytes, Luis M. Botana

Journal:

Journal of Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 173 KB

english, 2007

20

Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: Involvement of the c-Jun N-terminal kinase

Carmen Vale, Carolina Wandscheer, K.C. Nicolaou, Michael O. Frederick, Carmen Alfonso, Mercedes R. Vieytes, Luis M. Botana

Journal:

Journal of Neuroscience Research

Year:

2008

Language:

english

File:

PDF, 289 KB

english, 2008

21

Solid-Phase Radioreceptor Assay for Paralytic Shellfish Toxins

M.R. Vieytes, A.G. Cabado, A. Alfonso, M.C. Louzao, A.M. Botana, L.M. Botana

Journal:

Analytical Biochemistry

Year:

1993

File:

PDF, 549 KB

1993

22

A Fluorescent Microplate Assay for Diarrheic Shellfish Toxins

M.R. Vieytes, O.I. Fontal, F. Leira, J.M.V.Baptista de Sousa, L.M. Botana

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 127 KB

english, 1997

23

A Fluorescent Microplate Assay for Microcystin-LR

O.I. Fontal, M.R. Vieytes, J.M.V. Baptista de Sousa, M.C. Louzao, L.M. Botana

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 103 KB

english, 1999

24

A Fluorimetric Method Based on Changes in Membrane Potential for Screening Paralytic Shellfish Toxins in Mussels

M.C. Louzao, M.R. Vieytes, J.M.V. Baptista de Sousa, F. Leira, L.M. Botana

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 61 KB

english, 2001

25

A rapid microplate fluorescence method to detect yessotoxins based on their capacity to activate phosphodiesterases

Amparo Alfonso, Mercedes R Vieytes, Takeshi Yasumoto, Luis M Botana

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 224 KB

english, 2004

26

Quantification of yessotoxin using the fluorescence polarization technique and study of the adequate extraction procedure

Carmen Alfonso, Amparo Alfonso, Mercedes R. Vieytes, Takeshi Yasumoto, Luis M. Botana

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 476 KB

english, 2005

27

Extraction and cleaning methods to detect yessotoxins in contaminated mussels

C. Alfonso, A. Alfonso, M.J. Pazos, M.R. Vieytes, T. Yasumoto, A. Milandri, R. Poletti, L.M. Botana

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 509 KB

english, 2007

28

Functional assays for marine toxins as an alternative, high-throughput-screening solution to animal tests

Luis M. Botana, Amparo Alfonso, Ana Botana, Mercedes R. Vieytes, Carmen Vale, Natalia Vilariño, Carmen Louzao

Journal:

TrAC Trends in Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 166 KB

english, 2009

29

Inter-laboratory validation of the fluorescent protein phosphatase inhibition assay to determine diarrhetic shellfish toxins: intercomparison with liquid chromatography and mouse bioassay

J.C González, F Leira, O.I Fontal, M.R Vieytes, F.F Arévalo, J.M Vieites, M Bermúdez-Puente, S Muñiz, C Salgado, T Yasumoto, L.M Botana

Journal:

Analytica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 401 KB

english, 2002

30

Development of a F actin-based live-cell fluorimetric microplate assay for diarrhetic shellfish toxins

F Leira, C Alvarez, A.G Cabado, J.M Vieites, M.R Vieytes, L.M Botana

Journal:

Analytical Biochemistry

Year:

2003

Language:

english

File:

PDF, 220 KB

english, 2003

31

Development and validation of a high-performance liquid chromatographic method using fluorimetric detection for the determination of the diarrhetic shellfish poisoning toxin okadaic acid without chlorinated solvents

José C González, Francisco Leira, Mercedes R Vieytes, Juan M Vieites, Ana M Botana, Luis M Botana

Journal:

Journal of Chromatography A

Year:

2000

Language:

english

File:

PDF, 124 KB

english, 2000

32

Modified mass action law-based model to correlate the solubility of solids and liquids in entrained supercritical carbon dioxide

Jose C. González, Mercedes R. Vieytes, Ana M. Botana, Juan M. Vieites, Luis M. Botana

Journal:

Journal of Chromatography A

Year:

2001

Language:

english

File:

PDF, 367 KB

english, 2001

33

Non-immunological release of histamine from rat mast cells elicited by antineoplastic agents

L. M. Botana, E. Arnaez, M. R. Vieytes, A. Alfonso, M. J. Bujan, M. C. Louzao, A. Cabado

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 408 KB

english, 1992

34

Nonimmunological release of histamine from rat mast cells elicited by antineoplastic agents: effect of drug combinations

L. M. Botana, E. Arnaez, M. R. Vieytes, A. Alfonso, M. C. Louzao

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 543 KB

english, 1992

35

Study of the activation mechanism of human GRF(1-29)NH2on rat mast cell histamine release

M. D. Estévez, A. Alfonso, M. R. Vieytes, M. C. Louzao, L. M. Botana

Journal:

Inflammation Research

Year:

1995

Language:

english

File:

PDF, 566 KB

english, 1995

36

Study of the activation mechanism of adriamycin on rat mast cells

M. D. Estévez, M. R. Vieytes, L. M. Botana

Journal:

Inflammation Research

Year:

1994

Language:

english

File:

PDF, 579 KB

english, 1994

37

Influence of protein kinase C, cAMP and phosphatase activity on histamine release produced by compound 48/80 and sodium fluoride on rat mast cells

L. M. Botana, A. Alfonso, M. A. Botana, M. R. Vieytes, M. C. Louzao, A. G. Cabado

Journal:

Inflammation Research

Year:

1992

Language:

english

File:

PDF, 507 KB

english, 1992

38

Lack of specific saxitoxin binding to rat mast cells

M. R. Vieytes, M. C. Louzao, M. J. Bujan, A. Alfonso, A. Cabado, L. F. de la Cruz, L. M. Botana

Journal:

Inflammation Research

Year:

1991

Language:

english

File:

PDF, 141 KB

english, 1991

39

Changes in rat mast cell responses in sodium-free media. Lack of demonstrable sodium channel activity

M. R. Vieytes, A. Alfonso, M. J. Bujan, M. C. Louzao, A. Cavado, L. F. de la Cruz, L. M. Botana

Journal:

Inflammation Research

Year:

1991

Language:

english

File:

PDF, 237 KB

english, 1991

40

Mitoxantrone induces nonimmunological histamine release from rat mast cells

M. D. Estévez, M. R. Vieytes, L. M. Botana

Journal:

Inflammation Research

Year:

1996

Language:

english

File:

PDF, 533 KB

english, 1996

41

The antineoplastic drug vinorelbine activates non-immunological histamine release from rat mast cells

M. D. Estévez, M. R. Vieytes, M. C. Louzao, A. Alfonso, N. Vilariño, L. M. Botana

Journal:

Inflammation Research

Year:

1997

Language:

english

File:

PDF, 164 KB

english, 1997

42

Cytoskeletal disruption is the key factor that triggers apoptosis in okadaic acid-treated neuroblastoma cells

A.G. Cabado, F. Leira, M.R. Vieytes, J.M. Vieites, L.M. Botana

Journal:

Archives of Toxicology

Year:

2004

Language:

english

File:

PDF, 1.16 MB

english, 2004

43

Okadaic acid and dinophysis toxin 2 have differential toxicological effects in hepatic cell lines inducing cell cycle arrest, at G0/G1 or G2/M with aberrant mitosis depending on the cell line

J. A. Rubiolo, H. López-Alonso, F. V. Vega, M. R. Vieytes, L. M. Botana

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 970 KB

english, 2011

44

Determination of DSP toxins: comparative study of HPLC and bioassay to reduce the observation time of the mouse bioassay

J. M. Vieites, F. Leira, L. M. Botana, M. R. Vieytes

Journal:

Archives of Toxicology

Year:

1996

Language:

english

File:

PDF, 235 KB

english, 1996

45

Okadaic acid, a protein phosphatase inhibitor, stimulates the activity of Na+/H+and Na+-independent Cl–/HCO3–exchangers in human lymphocytes

L. de la Rosa, N. Vilariño, M. Vieytes, L. Botana

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2002

Language:

english

File:

PDF, 244 KB

english, 2002

46

Biological methods for marine toxin detection

Natalia Vilariño, M. Carmen Louzao, Mercedes R. Vieytes, Luis M. Botana

Journal:

Analytical and Bioanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

47

Evidence for an electrogenic, negatively protein-kinase-A-modulated, Na+-dependent HCO3–transporter in human lymphocytes

L. A. de la Rosa, A. G. Cabado, M. A. Botana, M. R. Vieytes, J. I. Vidal, L. M. Botana

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 142 KB

english, 1999

48

Confocal microscopy study of the different patterns of 2-NBDG uptake in rabbit enterocytes in the apical and basal zone

Yolanda Román, Amparo Alfonso, Carmen M. Louzao, Mercedes R. Vieytes, Luis M. Botana

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 148 KB

english, 2001

49

Profile for Amyloid-β and Tau Expression in Primary Cortical Cultures from 3xTg-AD Mice

Carmen Vale, Eva Alonso, Juan A. Rubiolo, Mercedes R. Vieytes, Frank M. LaFerla, Lydia Giménez-Llort, Luis M. Botana

Journal:

Cellular and Molecular Neurobiology

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

50

“Fluorescent glycogen” formation with sensibility forin vivoandin vitrodetection

M. Carmen Louzao, Begoña Espiña, Mercedes R. Vieytes, Felix V. Vega, Juan A. Rubiolo, Otto Baba, Tatsuo Terashima, Luis M. Botana

Journal:

Glycoconjugate Journal

Year:

2008

Language:

english

File:

PDF, 293 KB

english, 2008